Some knee pain is caused by the complex interplay of structural imbalances in your running gait. Other knee pain is caused by tripping and whacking your knee against something. For the second type of knee pain, the Wildhorse 4 is preventive medicine. It has a lugged, sticky rubber sole and protective rock plate to help you avoid falls and hazards underfoot, while the Phylon and Air sole with mesh and Flywire upper will keep you going the distance.