Although newer to the running shoe game, Topo has made a place for itself amongst the ranks for best running shoes. Topo specializes in natural running gear targeted for marathoners, triathletes, and obstacle racers. True to its name, the Fli-Lyte will let you soar with its minimalist design and weighing only 6.7 oz (women’s size 7). This shoe is flexible and well cushioned to give you a reliable companion on your runs.